(6-Bromo-3H-imidazo[4,5-b]pyridin-2-yl) - Names and Identifiers
Name | (6-bromo-1H-imidazo[4,5-b]pyridin-2-yl)methanol
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Synonyms | (6-Bromo-3H-imidazo[4,5-b]pyridin-2-yl) 6-Bromo-3H-imidazo[4,5-b]pyridine-2-methanol 6-Bromo-1H-imidazo[4,5-b]pyridine-2-methanol 3H-Imidazo[4,5-b]pyridine-2-methanol, 6-bromo- 3H-imidazo[4,5-b]pyridine-2-methanol, 6-bromo- (6-Bromo-3H-imidazo[4,5-b]pyridin-2-yl)methanol (6-bromo-3H-imidazo[4,5-b]pyridin-2-yl)methanol (6-bromo-1H-imidazo[4,5-b]pyridin-2-yl)methanol 6-Bromo-2-(hydroxymethyl)-3H-imidazo[4,5-b]pyridine
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CAS | 172648-19-0
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InChI | InChI=1/C7H6BrN3O/c8-4-1-5-7(9-2-4)11-6(3-12)10-5/h1-2,12H,3H2,(H,9,10,11) |
(6-Bromo-3H-imidazo[4,5-b]pyridin-2-yl) - Physico-chemical Properties
Molecular Formula | C7H6BrN3O
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Molar Mass | 228.05 |
Density | 1.927g/cm3 |
Melting Point | 230-233℃ |
Boling Point | 463.55°C at 760 mmHg |
Flash Point | 234.147°C |
Vapor Presure | 0mmHg at 25°C |
Storage Condition | 2-8°C |
Sensitive | IRRITANT |
Refractive Index | 1.763 |
MDL | MFCD09750272 |
(6-Bromo-3H-imidazo[4,5-b]pyridin-2-yl) - Introduction
(6-bromo-1H-imidazo[4,5-b]pyridin-2-yl)methanol is an organic compound with the chemical formula C9H5BrN2O. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: yellow or brown solid powder.
-Solubility: Soluble in common organic solvents (such as ethanol, ether and dichloromethane).
-Melting point: About 220-225 ℃.
-Stability: relatively stable under regular conditions.
Use:
- (6-bromo-1H-imidazo[4,5-b]pyridin-2-yl)methanol is an important intermediate compound that can be used in organic synthesis and pharmaceutical research.
Method:
The preparation of- (6-bromo-1H-imidazo[4,5-b]pyridin-2-yl)methanol usually involves a multi-step reaction. A common synthetic method is to react 2-bromo-6-aminoimidazo [4,5-b] Pyrimidine with a certain brominating agent (such as N-bromosuccinimide), then it is treated with alkaline solution to obtain 6-bromo-3H-imidazo [4,5-b] pyrimidine, and finally the target product (6-bromo-1H-imidazo[4,5-b]pyridin-2-yl)methanol is obtained by reduction.
Safety Information:
- (6-bromo-1H-imidazo[4,5-b]pyridin-2-yl)methanol should be used and stored in accordance with general laboratory safety procedures.
-The compound may be irritating to the eyes, skin and respiratory system, so wear appropriate personal protective equipment such as goggles, gloves and lab coats during operation.
-Avoid inhaling the dust or gas of the substance, and avoid direct contact with skin, eyes, etc.
-If you are exposed to this substance, immediately rinse the affected area with plenty of water and seek medical help.
-During storage, the substance should be stored in a sealed container, away from heat and fire sources, and avoid contact with oxidants and strong acids.
Last Update:2024-04-09 20:49:11